The problem is that there are so many different ways for an engine to fail:
- Excessive carbon buildup accelerates seal wear, causing compression loss
- Excessive carbon buildup unseats the apex seals, causing compression loss
- Excessive heat buildup warps the housings to one degree or another, preventing the apex seals from sealing, causing compression loss
- Excessive exhaust temperatures overheat the side seal springs, warping them until the side seal pops out of it's location, clips the exhaust port and shatters, throwing shrapnel through the engine (usually race motors, possible but rare in street motors)
- Fuel pump failure or high lateral G left turns with low fuel causes fuel starvation under load, creating a lean spike that causes detonation and shatters seals
- Cat failure (even more common than engine failure) causes localized heat and pressure buildup that overstresses the seals and breaks down oil viscosity, leading to various issues
- Clogged oil injection lines prevent oil from being injected, leading to excessive apex seal wear and side seal overheating, leading to compression loss and/or catastrophic failure (depending on which fails first)
- Subpar reman engine quality, starting with low compression that accelerates any other issue (reman quality has improved over the years, but bad apples are still reported)

These are just the common failure methods. There are uncommon ones, and/or freak ones, like a transmission issue snapped one guy's e-shaft somehow (probably a defective e-shaft that was too weak), or issues that are entirely owner caused, like too low octane or not keeping on top of the oil level.